Upstream refers to the material inputs needed for production, while downstream is the opposite end, where products get produced and distributed.
What is meant by downstream and upstream?
Stream – The moving water in a river is called a stream.
Upstream – If the boat is flowing in the opposite direction to the stream, it is called upstream. In this case, the net speed of the boat is called the upstream speed. Downstream – If the boat is flowing along the direction of the stream, it is called downstream.
What is upstream and downstream example?
As noted, upstream and downstream operations exist wherever there is a supply chain that begins with basic materials and ends with finished goods for sale. Therefore, another example of upstream to downstream can be the personal computer industry.
What are upstream processes?
Upstream process is the first step of bioprocess from early cell isolation and cultivation, to cell banking and culture development of the cells until final harvest where the desired quantity is reached. Since this is the early stage of bioprocessing, the quality of the product is of critical importance.
What is the difference between upstream and downstream applications?
In the case of upstream, we are looking at the application sending the data to another application. On the other hand, in the case of a downstream system, we are seeing that data flow in a different direction. In the case of downstream, we receive data.
What is the difference between upstream process and downstream process in protein production?
The key difference between upstream and downstream bioprocessing is that upstream bioprocessing involves screening and identification of microorganisms, media preparation, multiplication of microbes inside a bioreactor, and incubation, while downstream bioprocessing involves extraction, purification and packaging of …
What is upstream and downstream process in manufacturing?
Upstream processes are those in which biological materials are either obtained from an outside source or inoculated and grown in culture, under controlled conditions, to manufacture certain types of products. Downstream processes are those in which the products are harvested, tested, purified and packaged.
What is an example of downstream?
Downstream operations are the processes involved in converting oil and gas into the finished product. These include refining crude oil into gasoline, natural gas liquids, diesel, and a variety of other energy sources.
What is the difference between upstream and downstream in supply chain?
The upstream supply chain includes all activities related to the organization’s suppliers: those parties that source raw material inputs to send to the manufacturer. The downstream supply chain refers to activities post-manufacturing, namely distributing the product to the final customer.
What is downstream process in supply chain?
Downstream supply chain operations involve the movement of finished goods from a business to its customers. These operations include distribution, order fulfillment and delivery.
What is the difference between upstream and downstream in open source software development?
Within information technology, the term upstream (and related term “downstream”) refers to the flow of data. An upstream in open source is the source repository and project where contributions happen and releases are made. The contributions flow from upstream to downstream.
What is a downstream process in software development?
In software development, downstream refers to a direction away from the original authors or maintainers of software that is distributed as source code, and is a qualification of a patch. For example, a patch sent downstream is offered to the developers or maintainers of a forked software project.
What is downstream processing in data?
A downstream process is one that is processing personal data that has already been collected and is in a database somewhere within the organisation.
Which is downstream process?
Downstream processing is the recovery and purification of biochemical products with proper treatment. It is a series of events which includes cell separation, filtration, product recovery, extraction of product and purification and then treatment of product by chemical, physical and biological means.
What is downstream processing example?
Downstream processing refers to the recovery and the purification of biosynthetic products, particularly pharmaceuticals, from natural sources such as animal or plant tissue or fermentation broth, including the recycling of salvageable components and the proper treatment and disposal of waste.
Is fermentation upstream or downstream?
The fermentation or cell culture manufacturing process that is performed to generate the recombinant protein is referred to as the upstream process. Following the completion of upstream manufacturing, the material is transferred for downstream processing. This consists of purifying the recombinant protein.
What is upstream and downstream processing in oil and gas?
While upstream entails the initial phases of oil and gas production, downstream encompasses the final phases including refining and distribution of finished products like gasoline to consumers. In general, the farther a part of the process is from the end-user consumer, the more upstream it is.
Why do we need downstream processing?
The purpose of downstream processing is to isolate, purify and concentrate the previously synthesized drug substance or other product from the complex bulk matrix. Downstream processing may also include formulation activities, signifying the transition from drug substance to drug product (DP).