Convention for selection of summary slices in fMRI?

How many slices are in fMRI?

How many slices? The default of 32 slices will cover most of the brain in most subjects. However, if you are also interested in the cerebellum, 36 slices is recommended (this results in a 2.19 second TR).

How is fMRI data collected?

As concisely summarized in Savoy (2001), fMRI involves collecting data of brain activation by taking advantage of a series of connection in the brain: how neural activity (electrical and chemical events) is connected to changes in brain physiology and metabolism which in turn links to changes in the magnetic properties …

How many voxels are in fMRI?

Typically, fMRI machines divide the brain into three-dimensional pixels called voxels, each about five cubic millimeters in size. The complete activity of the brain at any instant can be recorded using a three-dimensional grid of 60 x 60 x 30 voxels.

Why is T2 * contrast used for fMRI?

The relaxation time in this case is denoted as T2*, which basically results from the non-uniformity of the main magnetic field resulted from local magnetic gradient. T2*-weighted MRI sequences are used to highlight the magnetic uniformity effects to generate high contrast images through fMRI.

What is a slice in fMRI?

Unlike a photograph, in which the entire picture is taken in a single moment, an fMRI volume is acquired in slices. Each of these slices takes time to acquire – from tens to hundreds of milliseconds. The two most commonly used methods for creating volumes are sequential and interleaved slice acquisition.

What is slice timing correction?

Slice timing correction (STC) is the preprocessing step applied to correct for these slice-dependent delays, achieved by shifting the time series of each slice to temporally align all slices to a reference time-point.

What does fNIRS measure?

Functional near-infrared spectroscopy (fNIRS) is a non-invasive brain imaging technique that measures blood oxygenation changes similar to fMRI. The technique is based upon the changes in absorption of light emitted by sources onto the surface of the head and measured by detectors.

What is the temporal resolution of fMRI?

Temporal resolution refers to the accuracy of the scanner in relation of time: or how quickly the scanner can detect changes in brain activity. fMRI scans have a temporal resolution of 1-4 seconds which is worse than other techniques (e.g. EEG/ERP which have a temporal resolution of 1-10 milliseconds).

What are the limitations of fMRI?

Yet fMRI also has its disadvantages. First, it’s expensive. Second, it can only capture a clear image if the person being scanned stays completely still. And third, researchers still don’t completely understand how it works.

What is spin echo sequence?

The spin echo sequence is made up of a series of events : 90° pulse – 180° rephasing pulse at TE/2 – signal reading at TE. This series is repeated at each time interval TR (Repetition time). With each repetition, a k-space line is filled, thanks to a different phase encoding.

What is T1 and T2 in fMRI?

The most common MRI sequences are T1-weighted and T2-weighted scans. T1-weighted images are produced by using short TE and TR times. The contrast and brightness of the image are predominately determined by T1 properties of tissue. Conversely, T2-weighted images are produced by using longer TE and TR times.

What is the difference between T2 and T2 * images?

T2* can be considered an “observed” or “effective” T2, whereas the first T2 can be considered the “natural” or “true” T2 of the tissue being imaged. T2* is always less than or equal to T2. T2* results principally from inhomogeneities in the main magnetic field.

How is spin-echo formed?

In fact, spin echoes are formed when two successive RF-pulses of any flip angle are employed! Hahn, in his original paper, used two 90° pulses. When flip angles other than 90° and 180° are employed, the resultant spin echo is sometimes referred to as a Hahn echo.

What is the difference between spin-echo and gradient echo?

A spin echo (SE) is produced by pairs of radiofrequency (RF) pulses, whereas a gradient echo (GRE) is produced by a single RF pulse in conjunction with a gradient reversal. The formation of a GRE is illustrated schematically.

What is MRI stir for?

The role of the STIR sequence in detection of recurrences in the post-surgical follow-up was also evaluated. The STIR sequence, designed to suppress signal from fat, also enhances the signal from tissue with long T1 and T2 relaxation times, such as neoplastic and inflammatory tissue.

What is T2 and stir?

Abstract. T2-weighted short-tau inversion recovery (T2w-STIR) imaging is the best approach for oedema-weighted cardiac magnetic resonance imaging (MRI), as it suppresses the signal from flowing blood and from fat and enhances sensitivity to tissue fluid.

Is stir a T1 or T2?

What is STIR? STIR stands for Short-TI Inversion Recovery and is typically used to null the signal from fat. At 1.5T fat has a T1 value of approximately 260 ms, so its TInull value is approximately 0.69 x 250 = 180 ms.

Is STIR sequence T1 or T2?

STIR sequences

Fat has a short T1. Hence by choosing a short TI of 140 milliseconds, the fat signal can be suppressed . The combination of short TI inversion-recovery and fast spin echo sequences reduces acquisition time to acceptable limits for clinical practice.

What is stir signal?

Short tau inversion recovery (STIR), also known as short TI inversion recovery, is a fat suppression technique with an inversion time TI = ln(2)·T1fat, where the signal of fat is zero. This equates to approximately 140 ms at 1.5 T.

What is hyperintense on STIR MRI?

Hyperintensity is a term used in MRI reports to describe how part of an image looks on MRI scan. Most MRIs are in black/white with shades of gray. A hyperintensity is an area that appears lighter in color than the surrounding tissues; a hypointensity would be darker in color.

What is T2 and FLAIR Hyperintensities?

Focal hyperintensities in the subcortical white matter demonstrated by T2-weighted or FLAIR images are a common incidental finding in patients undergoing brain MRI for indications other than stroke. They are indicative of chronic microvascular disease.

What is foci of T2 hyperintensity?

Background: T2-hyperintense foci are one of the most frequent findings in cerebral magnetic resonance imaging (MRI). They can pose serious diagnostic problems which is reflected by their English name and abbreviation – UBOs (Unidentified Bright Objects).

What does Leukoaraiosis mean?

Background— Leukoaraiosis, a term that defines an abnormal appearance of the subcortical white matter of the brain on neuroimaging (bilateral patchy or diffuse areas of low attenuation on CT or hyperintense T2 MR areas), has gained evidence in retrospective studies to demonstrate its association with stroke and in …

What does moderate leukoaraiosis mean?

Leukoaraiosis is a pathological appearance of the brain white matter, which has long been believed to be caused by perfusion disturbances within the arterioles perforating through the deep brain structures.

What does mild leukoaraiosis mean?

Mild cognitive impairmentWhite matter lesionsLeukoaraiosisDementia. Mild cognitive impairment (MCI) refers to a clinical state between normal ageing and dementia that does not meet the diagnostic criteria for dementia.